Mosaic
Digital Illumination System
The Mosaic Digital Illumination Systems uses a computer controlled spatial light modulator to map a diffraction limited mask onto the specimen plane. In combination with its continuous wave (CW) laser or arc lamp light fluorescence excitation sources, it accommodates laser scanning confocal, spinning disk confocal and widefield microscopes.
Discover what you are missing
With Mosaic’s true digital illumination, it is possible to simultaneously and precisely excite multiple regions of interest with complex geometries in real time and with zero delta acquisition time - realizing true digital illumination. These benefits are demonstrated today in combination with laser scanning and spinning disk confocal as well as wide field fluorescence microscopy. In combination with the widefield is the ability to not only monitor rapidly occurring events within living cells, but to optimize illumination further reducing the effects of photobleaching and phototoxicity. For some biological assays, wide field microscopy is still preferred over higher resolution confocal imaging, because it provides better and greater depth of the field. When entire sample areas are illuminated and imaged using such a microscope, secondary fluorescence emitted by the specimen often interferes with the resolution of those features that are in focus. Mosaic's true digital excitation eliminates the interference of unwanted secondary fluorescence within the regions of interest.
Life Sciences
- FRAP
- FRET
- Photoactivation
- Photobleaching
- Photoswitching
- Photoconverting
- Cell Regeneration/Degeneration
- Release of Caged Compounds
- Drug Delivery
- Thrombosis
- Free Radical Release
- CALI
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